Abstract
Three new chlorine-containing beta-carbolines, bauerines A-C (1-3), have been isolted from the terrestrial blue-green alga Dichothrix baueriana GO-25-2, and identifying mass and nmr spectral analysis. The alkaloids show activity against herpes simplex virus type 2.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Antiviral Agents / pharmacology*
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Carbolines / isolation & purification*
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Carbolines / pharmacology
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Cells, Cultured
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Cyanobacteria / chemistry*
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Drug Screening Assays, Antitumor
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Herpesvirus 2, Human / drug effects
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Humans
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mink
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Tumor Cells, Cultured
Substances
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Antiviral Agents
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Carbolines
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bauerine A
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bauerine B
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bauerine C