N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters

J Med Chem. 1994 May 27;37(11):1558-61. doi: 10.1021/jm00037a004.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Behavior, Animal / drug effects
  • Brain / metabolism*
  • Carrier Proteins / metabolism*
  • Cocaine / analogs & derivatives*
  • Cocaine / chemistry
  • Cocaine / metabolism
  • Dopamine Plasma Membrane Transport Proteins
  • Female
  • Iodine Radioisotopes*
  • Kinetics
  • Male
  • Membrane Glycoproteins*
  • Membrane Transport Proteins*
  • Nerve Tissue Proteins*
  • Neurons / metabolism*
  • Papio
  • Rats
  • Rats, Sprague-Dawley
  • Tomography, Emission-Computed*
  • Tomography, Emission-Computed, Single-Photon*
  • Tropanes / chemical synthesis*
  • Tropanes / metabolism
  • Tropanes / pharmacology

Substances

  • Carrier Proteins
  • Dopamine Plasma Membrane Transport Proteins
  • Iodine Radioisotopes
  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Nerve Tissue Proteins
  • Tropanes
  • 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
  • 2beta-carbomethoxy-3beta-(4-iodophenyl)tropane
  • Cocaine