Still's disease relapse with severe pneumonitis after prolonged remission

Intern Med. 1993 Dec;32(12):902-5. doi: 10.2169/internalmedicine.32.902.

Abstract

A 20-year-old woman who had suffered from Still's disease was admitted for fever and progressive pneumonitis after long-term remission. High spiking fever, leukocytosis, splenomegaly and an extremely high serum ferritin concentration strongly suggested a relapse of Still's disease. Intensive therapy with high-dose methylprednisolone, cyclophosphamide and gamma globulin was required for the severe pneumonitis, which was thought to be a rare manifestation in Still's disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthritis, Juvenile / complications*
  • Arthritis, Juvenile / diagnosis
  • Arthritis, Juvenile / therapy
  • Cyclophosphamide / administration & dosage
  • Female
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage
  • Methylprednisolone / administration & dosage
  • Pneumonia / complications*
  • Pneumonia / diagnosis
  • Pneumonia / therapy
  • Recurrence
  • Respiratory Insufficiency / complications
  • Thrombocytopenia / complications
  • Time Factors

Substances

  • Immunoglobulins, Intravenous
  • Cyclophosphamide
  • Methylprednisolone