Phellodonic acid, a new biologically active hirsutane derivative from Phellodon melaleucus (Thelephoraceae, Basidiomycetes)

Z Naturforsch C J Biosci. 1993 Jul-Aug;48(7-8):545-9. doi: 10.1515/znc-1993-7-803.

Abstract

A new hirsutane derivative, phellodonic acid (1), has been isolated from fermentations of Phellodon melaleucus strain 87113. Its structure was elucidated by spectroscopic methods. The compound exhibits antibiotic activities towards bacteria and fungi. 1 is the first bioactive metabolite from cultures of a species belonging to the family Thelephoraceae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / toxicity*
  • Bacteria / drug effects*
  • Basidiomycota / chemistry*
  • Basidiomycota / growth & development
  • Caprylates / chemistry
  • Caprylates / isolation & purification
  • Caprylates / toxicity
  • Chlorella / drug effects
  • Fermentation
  • Fungi / drug effects*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification
  • Sesquiterpenes / toxicity

Substances

  • Anti-Bacterial Agents
  • Caprylates
  • Sesquiterpenes
  • phellodonic acid