Abstract
A number of adamantaneketoxime ethers and an acetylenic adamantaneketoxime iododerivative have been prepared and tested as potential antifungal agents. They were also examined for their antibacterial and antiviral effects. Most of them proved active against the tested fungi. Their antimicrobial activity was generally low, while they did not exhibit a "specific" antiviral activity against any of the viruses tested.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adamantane / analogs & derivatives*
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Adamantane / chemical synthesis*
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Adamantane / pharmacology
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Anti-Bacterial Agents
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Anti-Infective Agents / chemical synthesis*
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Anti-Infective Agents / pharmacology
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Antifungal Agents / chemical synthesis
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Antifungal Agents / pharmacology
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Antiviral Agents / chemical synthesis
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Antiviral Agents / pharmacology
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Bacteria / drug effects
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Fungi / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Oximes / chemical synthesis*
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Oximes / pharmacology
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Spectrophotometry, Infrared
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Viruses / drug effects
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Antifungal Agents
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Antiviral Agents
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Oximes
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Adamantane