Aggressive angiomyxoma of the pelvioperineal region. Immunohistological and ultrastructural study of seven cases

Am J Dermatopathol. 1993 Oct;15(5):446-51. doi: 10.1097/00000372-199310000-00006.

Abstract

We describe seven cases of aggressive angiomyxoma of the pelvioperineal region. In three cases, we observed immunohistochemical signs of myoid differentiation in the tumor cells. In one of these cases, we could confirm the myoid differentiation at the ultrastructural level. The other four cases were devoid of this differentiation. We further discuss the relationship of aggressive angiomyxoma to the recently described angiomyofibroblastoma of the vulva.

MeSH terms

  • Actins / analysis
  • Adipose Tissue / pathology
  • Adult
  • Collagen / analysis
  • Desmin / analysis
  • Extracellular Matrix / ultrastructure
  • Female
  • Fibroblasts / pathology
  • Humans
  • Immunoenzyme Techniques
  • Laminin / analysis
  • Microscopy, Electron
  • Middle Aged
  • Muscle, Smooth / pathology
  • Myxoma / blood supply
  • Myxoma / pathology*
  • Myxoma / ultrastructure
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local
  • Pelvic Neoplasms / blood supply
  • Pelvic Neoplasms / pathology*
  • Pelvic Neoplasms / ultrastructure
  • Vulvar Neoplasms / blood supply
  • Vulvar Neoplasms / pathology*
  • Vulvar Neoplasms / ultrastructure

Substances

  • Actins
  • Desmin
  • Laminin
  • Collagen