The manufacture and molecular characterization of phosphorothioate deoxynucleotides for use as antisense therapeutics in human clinical trials

Nucleic Acids Symp Ser. 1993:(29):57.

Authors

B J Bergot¹, M Foy, C Hansen, K Fearon, J Frediani, B Hirschbein

Affiliation

¹ Lynx Therapeutics, Inc., Foster City, CA 94404.

PMID: 8247794

No abstract available

MeSH terms

Clinical Trials, Phase I as Topic
DNA, Antisense / chemical synthesis*
DNA, Antisense / genetics
DNA, Antisense / therapeutic use
Deoxyribonucleotides / chemistry*
Deoxyribonucleotides / genetics
Deoxyribonucleotides / therapeutic use
Gene Expression Regulation
Genes, p53
Humans
Leukemia, Myeloid, Acute / drug therapy*
Thionucleotides / chemical synthesis*
Thionucleotides / genetics
Thionucleotides / therapeutic use

Substances

DNA, Antisense
Deoxyribonucleotides
Thionucleotides