Carney's triad: apropos of a new case

Med Pediatr Oncol. 1994;22(3):216-20. doi: 10.1002/mpo.2950220313.

Abstract

Carney's triad is defined by the coexistence of at least two of three rare disorders, including gastric epithelioid leiomyosarcoma (malignant leiomyoblastoma), pulmonary chondroma, and paraganglioma, most often extra-adrenal and functioning. We report a new case in a 10-year-old girl. The paraganglioma, although nonfunctioning, was detected after it was searched for, as Carney's triad was suspected. Unrelated seems the development of breast fibroadenomas in the same patient. Whenever a patient with one component of the triad is encountered, the possibility of this syndrome should be considered and the other two components sought.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Breast Neoplasms / pathology
  • Child
  • Chondroma
  • Female
  • Fibroadenoma / pathology
  • Humans
  • Leiomyosarcoma
  • Lung Neoplasms / pathology*
  • Mediastinal Neoplasms
  • Neoplasms, Multiple Primary / pathology*
  • Paraganglioma, Extra-Adrenal / pathology*
  • Stomach Neoplasms / pathology*
  • Syndrome