Dynamic properties of cortical evoked (10 Hz) oscillations: theory and experiment

Biol Cybern. 1993;69(5-6):463-73.

Abstract

Experiments probed the dynamic properties of stimulus-evoked (approximately 10 Hz) oscillations in somatosensory cortex of anesthetized rats. Experimental paradigms and statistical time series analysis were based on theoretical ideas from a dynamic approach to temporal patterns of neuronal activity. From the results of a double-stimulus paradigm we conclude that the neuronal response contains two components with different dynamics and different coupling to the stimulus. Based on this result a quantitative dynamic model is derived, making use of normal form theory for bifurcating vector fields. The variables used are abstract, but measurable, dynamic components. The model parameters capture the dynamic properties of neuronal response and are related to experimental results. A structural interpretation of the model can be given in terms of the collective dynamics of neuronal groups, their mutual interaction, and their coupling to peripheral stimuli. The model predicts the stimulus-dependent lifetime of the oscillations as observed in experiment. We show that this prediction relies on the basic concept of dynamic bistability and does not depend on the modeling details.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Electric Stimulation
  • Evoked Potentials, Somatosensory / physiology*
  • Mathematics
  • Models, Neurological*
  • Neurons / physiology*
  • Oscillometry
  • Rats
  • Somatosensory Cortex / physiology*