Multiple familial glomangiomas are rare vascular tumours, which are inherited as an autosomal dominant trait. They usually arise at puberty or later, and may involve all parts of the skin. In contrast to solitary glomangiomas, they are not painful. Histopathologically, they are characterized by widely dilated vascular spaces, surrounded by only a few glomus cells. In a report on two patients, the clinical, histopathological and immunocytochemical features and the differential diagnosis of multiple familial glomangiomas are discussed.