Case report of acquired piritrexim resistance and collateral methotrexate sensitivity in recurrent squamous cell carcinoma of the head and neck

J Natl Cancer Inst. 1993 Aug 4;85(15):1248. doi: 10.1093/jnci/85.15.1248.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Squamous Cell / drug therapy*
  • Drug Resistance
  • Folic Acid Antagonists / therapeutic use*
  • Head and Neck Neoplasms / drug therapy*
  • Humans
  • Male
  • Methotrexate / therapeutic use*
  • Neoplasm Recurrence, Local / drug therapy
  • Pyrimidines / therapeutic use*

Substances

  • Antineoplastic Agents
  • Folic Acid Antagonists
  • Pyrimidines
  • piritrexim
  • Methotrexate