A prospective research project on health education about AIDS is being conducted in the Greater Athens area. In the first phase of the project, information was collected concerning the knowledge and attitudes about AIDS of a sample of the population. The results indicated that, in general, the population was moderately well informed about AIDS. The population groups who were best informed were the females, those with a higher level of education and a longer period of urban residence, and those in the occupational category merchants/sales personnel. Three attitudinal categories were identified which could be characterized as discrimination, stigmatization and fear of those affected by AIDS. These attitudes were linked respectively to: (1) approval of the enforcement of special measures, (2) stigmatizing of persons, behaviours and districts and (3) fear that AIDS comprises a major social threat. The attitudes expressed by restrictive measures towards those affected and stigmatization were associated with a low level of knowledge about most aspects of AIDS. Health education programmes directed at the population in the districts studied should take into account the findings of this study.