Abstract
The purpose of the present study was to follow the development of periapical lesions both radiographically and histologically in infected teeth with open and sealed root canals. The mandibular premolars from five adult monkeys were used in the experiment. Sealed infected teeth developed radiographic signs of periapical pathosis significantly earlier than unsealed teeth. Although, histological signs of pathology could be seen periapically at earlier observation periods, sealed teeth consistently developed these changes earlier than unsealed teeth. Furthermore, the histological periapical pathology differed somewhat between the two groups in that unsealed teeth showed a multi-focal diffuse pattern of spreading.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Dental Plaque / microbiology
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Dental Pulp Cavity / diagnostic imaging
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Dental Pulp Cavity / microbiology
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Dental Pulp Cavity / pathology
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Granulation Tissue / diagnostic imaging
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Granulation Tissue / pathology
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Macaca fascicularis
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Necrosis
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Periapical Diseases / diagnostic imaging
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Periapical Diseases / etiology*
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Periapical Diseases / pathology
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Periapical Granuloma / diagnostic imaging
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Periapical Granuloma / etiology
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Periapical Granuloma / pathology
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Periapical Tissue / blood supply
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Periapical Tissue / diagnostic imaging
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Periapical Tissue / pathology
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Radicular Cyst / diagnostic imaging
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Radicular Cyst / etiology
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Radicular Cyst / pathology
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Radiography
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Root Canal Obturation
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Zinc Oxide-Eugenol Cement
Substances
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Zinc Oxide-Eugenol Cement