The 3D structure of glucose oxidase from Aspergillus niger. Implications for the use of GOD as a biosensor enzyme

H J Hecht; D Schomburg; H Kalisz; R D Schmid

doi:10.1016/0956-5663(93)85033-k

The 3D structure of glucose oxidase from Aspergillus niger. Implications for the use of GOD as a biosensor enzyme

Biosens Bioelectron. 1993;8(3-4):197-203. doi: 10.1016/0956-5663(93)85033-k.

Authors

H J Hecht¹, D Schomburg, H Kalisz, R D Schmid

Affiliation

¹ Gesellschaft für Biotechnologische Forschung (GBF), Department of Molecular Structure Research, Braunschweig, Germany.

PMID: 8357574
DOI: 10.1016/0956-5663(93)85033-k

Abstract

The tertiary structure of glucose oxidase (GOD) from Aspergillus niger was determined by x-ray crystallography (to be described elsewhere). The overall folding of the enzyme is described with regard to its application in biosensors, and conclusions are drawn from experiments on electrical communication between the enzyme and the electrodes.

MeSH terms

Aspergillus niger / enzymology*
Binding Sites
Biosensing Techniques*
Glucose / analysis*
Glucose Oxidase / chemistry*
Glucose Oxidase / isolation & purification
Glucose Oxidase / metabolism
Models, Molecular
Protein Folding
Protein Structure, Secondary*
Protein Structure, Tertiary*
X-Ray Diffraction

Substances

Glucose Oxidase
Glucose