Abstract
The clinical, pathological and laparoscopic data of five patients with liver disease due to Thorotrast are presented. Laparoscopy showed various degrees of fibrosis and nodularity. One patient developed cholangiocarcinoma and two showed dysplasia at biopsy. The laparoscopic appearance is practically diagnostic.
MeSH terms
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Adenoma, Bile Duct / chemically induced
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Adenoma, Bile Duct / pathology
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Aged
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Bile Duct Neoplasms / chemically induced
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Bile Duct Neoplasms / pathology
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Biopsy
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Bone Neoplasms / chemically induced
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Bone Neoplasms / pathology
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Carcinoma, Hepatocellular / chemically induced
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Carcinoma, Hepatocellular / pathology
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Chemical and Drug Induced Liver Injury*
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Female
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Fibrosis / chemically induced
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Fibrosis / pathology
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Humans
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Laparoscopy
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Liver / drug effects
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Liver / pathology
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Liver Diseases / pathology
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Liver Neoplasms / chemically induced
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Liver Neoplasms / pathology
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Male
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Middle Aged
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Osteosarcoma / chemically induced
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Osteosarcoma / pathology
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Thorium Dioxide / adverse effects*