Rapid immunophenotypic characterization of chromosomally aberrant cells by the new FICTION method

K Weber-Matthiesen; J Deerberg; A Müller-Hermelink; B Schlegelberger; W Grote

doi:10.1159/000133515

Rapid immunophenotypic characterization of chromosomally aberrant cells by the new FICTION method

Cytogenet Cell Genet. 1993;63(2):123-5. doi: 10.1159/000133515.

Authors

K Weber-Matthiesen¹, J Deerberg, A Müller-Hermelink, B Schlegelberger, W Grote

Affiliation

¹ Institut für Humangenetik, Klinikum der Christian-Albrechts-Universität, Kiel, FRG.

PMID: 8385597
DOI: 10.1159/000133515

Abstract

Recently, we have presented a new technique for immunophenotyping cells that have numerical chromosome aberrations. We referred to this method as "Fluorescence-Immunophenotyping and Interphase Cytogenetics as a Tool for Investigation of Neoplasms" (FICTION). We present here an advanced FICTION method with three-color staining and improved sensitivity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antigens, CD / analysis
Antigens, Neoplasm / analysis
CD3 Complex / analysis
Chromosome Aberrations*
Female
Hodgkin Disease / genetics
Humans
Immunophenotyping / methods*
In Situ Hybridization, Fluorescence
Karyotyping
Ki-1 Antigen
Male
Sensitivity and Specificity

Substances

Antigens, CD
Antigens, Neoplasm
CD3 Complex
Ki-1 Antigen