Expression of equine herpesvirus 1 glycoprotein D by using a recombinant baculovirus

J Virol. 1993 Nov;67(11):6820-3. doi: 10.1128/JVI.67.11.6820-6823.1993.

Abstract

Glycoprotein D (gD) of equine herpesvirus 1 (EHV-1) was expressed at the surface of insect cells infected by a recombinant baculovirus. EHV-1 gD was detected as multiple forms (56, 52, and 48 kDa) from 18 to 96 h postinfection. Laboratory animals inoculated with the recombinant EHV-1 gD developed neutralizing antibody responses against both EHV-1 and EHV-4.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cloning, Molecular
  • Fluorescent Antibody Technique
  • Herpesvirus 1, Equid / genetics*
  • Herpesvirus 1, Equid / immunology
  • Moths
  • Neutralization Tests
  • Nucleopolyhedroviruses / genetics
  • Viral Envelope Proteins / chemistry
  • Viral Envelope Proteins / genetics*
  • Viral Envelope Proteins / immunology

Substances

  • Viral Envelope Proteins
  • glycoprotein D, Equid herpesvirus 1