Use of imipenem in the treatment of pulmonary nocardiosis

Chest. 1993 Mar;103(3):951-2. doi: 10.1378/chest.103.3.951.

Abstract

A case of pulmonary nocardiosis with empyema in a 55-year-old man with macroglobulinemic lymphoma is presented. Treatment with imipenem followed by oral trimethoprim-sulfamethoxazole (TMP-SMX) resolved his symptoms and cleared the roentgenographic abnormalities. This case illustrates the clinical potential of imipenem against Nocardia.

Publication types

  • Case Reports

MeSH terms

  • Drug Therapy, Combination
  • Empyema / complications
  • Empyema / drug therapy
  • Humans
  • Imipenem / therapeutic use*
  • Lung Diseases / complications
  • Lung Diseases / drug therapy*
  • Lung Neoplasms / complications
  • Lymphoma / complications
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Nocardia Infections / complications
  • Nocardia Infections / drug therapy*
  • Nocardia asteroides* / drug effects
  • Nocardia asteroides* / isolation & purification
  • Opportunistic Infections / complications
  • Opportunistic Infections / drug therapy
  • Stomach Neoplasms / complications
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
  • Waldenstrom Macroglobulinemia / complications

Substances

  • Imipenem
  • Trimethoprim, Sulfamethoxazole Drug Combination