A trans-platinum complex showing higher antitumor activity than the cis congeners

J Med Chem. 1993 Feb 19;36(4):510-2. doi: 10.1021/jm00056a012.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / chemical synthesis*
  • Antineoplastic Agents / therapeutic use
  • Cisplatin / chemistry*
  • Cisplatin / therapeutic use
  • DNA / metabolism
  • Ethers / chemistry
  • Imines / chemistry
  • Leukemia P388 / drug therapy
  • Mice
  • Molecular Structure
  • Stereoisomerism

Substances

  • Antineoplastic Agents
  • Ethers
  • Imines
  • transplatin
  • DNA
  • Cisplatin