101 patients being treated for end-stage renal failure were studied in order to get the variables that are involved with psychosocial adaptation. Stepwise logistic regression analysis was made using the psychosocial adaptation as a dependent variable, determined by the Axis V of the D.S.M-III. 40 patients were found socially-adapted and 61 were not. Nine variables were related with the psychosocial adaptation: marital status, religious belief, education level, occupation, means of transportation to get to the treatment center, self-image before the sickness, C factor of 16 PF, the age and the evaluation of treatment by the patient. From the statistical analysis and from the interpretation of sings and values of the related variables, the influence of them on the psychosocial adaptation was demonstrated.