In 53 patients with peripheral facial palsy divided in the definite groups there have been continually followed up changes in the physico-chemical features of saliva of the submandibular salivary glands and the motor function of the mimic musculature in the course of a year-observation of pH, osmotic pressure and electrolöte secretion. The reduction of Na+ and CO2 secretion resulted in the low values of pH and osmotic pressure in all saliva samples at the site of lesion. The degree of this reduction has been shown to be in the direct relationship with the severity of the nerve lesion and its final outcome.