Abstract
Twenty-three children, aged 3 to 15 years, with chronic delta hepatitis have been followed for 5 to 12 years to evaluate long-term outcome. Although 83% of patients had chronic active hepatitis when first seen, with cirrhosis in 26%, the clinical and biochemical features of the disease remained reasonably stable during observation; liver histologic findings, obtained in 14 patients, worsened in only two.
MeSH terms
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Adolescent
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Child
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Child, Preschool
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Female
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Follow-Up Studies
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Hepatitis D / pathology
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Hepatitis D / physiopathology*
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Hepatitis D / therapy
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Hepatitis, Chronic / pathology
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Hepatitis, Chronic / physiopathology*
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Hepatitis, Chronic / therapy
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Humans
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Interferon Type I / therapeutic use
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Liver / pathology
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Male
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Recombinant Proteins
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Remission Induction
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Remission, Spontaneous
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Time Factors
Substances
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Interferon Type I
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Recombinant Proteins