Occurrence of primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome in a patient with HTLV-I-associated myelopathy

J Neurol Sci. 1993 May;116(1):47-51. doi: 10.1016/0022-510x(93)90088-g.

Abstract

We report the occurrence of three autoimmune diseases (primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome) in a patient with HTLV-I-associated myelopathy (HAM). The patient had the depressed cell-mediated immune responses but the infiltration of CD8-T cells was found in the cerebrospinal fluid and liver. The clinical and immunological features of this case are similar to those of chronic graft-versus-host disease.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • CD8 Antigens / analysis
  • Female
  • HTLV-I Infections / complications*
  • HTLV-I Infections / immunology
  • HTLV-I Infections / pathology
  • Humans
  • Liver / pathology
  • Liver Cirrhosis, Biliary / complications*
  • Liver Cirrhosis, Biliary / immunology
  • Liver Cirrhosis, Biliary / pathology
  • Lymphocytes / immunology*
  • Middle Aged
  • Radiography
  • Scleroderma, Localized / complications*
  • Scleroderma, Localized / immunology
  • Scleroderma, Localized / pathology
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / immunology
  • Sjogren's Syndrome / pathology
  • Spinal Cord / diagnostic imaging
  • Spinal Cord / pathology*
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocyte Subsets / pathology

Substances

  • CD8 Antigens