Substituted 2-azaspiro[5.3]nonan-1-ones as potent cholesterol absorption inhibitors: defining a binding conformation for SCH 48461

J Med Chem. 1995 Dec 8;38(25):4875-7. doi: 10.1021/jm00025a002.
No abstract available

MeSH terms

  • Animals
  • Anticholesteremic Agents / chemical synthesis
  • Anticholesteremic Agents / chemistry*
  • Anticholesteremic Agents / pharmacology
  • Azetidines / chemical synthesis
  • Azetidines / chemistry*
  • Azetidines / pharmacology
  • Cricetinae
  • Drug Design
  • Models, Molecular
  • Molecular Conformation
  • Structure-Activity Relationship

Substances

  • Anticholesteremic Agents
  • Azetidines
  • 1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone