Isradipine, a calcium-channel antagonist, has immunosuppressor activity on T lymphocytes from peripheral blood and synovial fluid from patients with autoimmune arthritis

J Immunother Emphasis Tumor Immunol. 1995 Jul;18(1):66-74. doi: 10.1097/00002371-199507000-00009.

Authors

C Guillen¹, A Prieto, M Alvarez De Buergo, L Villa, H Rico, A Zea, M P Hernandez, M Alvarez-Mon

Affiliation

¹ Servicio de Enfermedades del Sistema Immune, Hospital Universitario Príncipe de Asturias, Spain.

PMID: 8535573
DOI: 10.1097/00002371-199507000-00009

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Arthritis / blood
Arthritis / drug therapy*
Arthritis / immunology
Autoimmune Diseases / blood
Autoimmune Diseases / drug therapy*
Autoimmune Diseases / immunology
Calcium Channel Blockers / pharmacology
Calcium Channel Blockers / therapeutic use
Female
Humans
Immunosuppressive Agents / pharmacology*
Immunosuppressive Agents / therapeutic use
Isradipine / pharmacology*
Isradipine / therapeutic use
Lymphocyte Activation / drug effects
Male
Synovial Fluid / drug effects
Synovial Fluid / immunology*
T-Lymphocytes / drug effects*
T-Lymphocytes / immunology

Substances

Calcium Channel Blockers
Immunosuppressive Agents
Isradipine