MR spectroscopic imaging of collagen: tendons and knee menisci

Magn Reson Med. 1995 Nov;34(5):647-54. doi: 10.1002/mrm.1910340502.

Abstract

Water molecules associated with collagen have short transverse (T2) relaxation times. Projection-reconstruction techniques are able to achieve an echo time (TE) much shorter than conventional techniques, allowing imaging of tissues with T2 < 5 ms. Using these techniques, a conventional 1.5-T MRI human imaging system can directly image collagen-associated water from knee menisci and tendons in normal volunteers and patients. Long-T2 suppression improves the contrast between these structures and the surrounding tissue with long-T2 relaxation times. Spectroscopic imaging provides improved lipid/water registration and information about chemical composition and relaxation times. Direct imaging of tendons and menisci may provide more information about these structures and provide a new way to assess both injury and repair.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Collagen*
  • Humans
  • Image Processing, Computer-Assisted
  • Knee Injuries / diagnosis
  • Knee Joint / anatomy & histology*
  • Knee Joint / pathology
  • Magnetic Resonance Spectroscopy* / methods
  • Menisci, Tibial / anatomy & histology*
  • Menisci, Tibial / pathology
  • Tendons / anatomy & histology*
  • Tendons / pathology

Substances

  • Collagen