Peripheral primitive neuroectodermal tumour after allogeneic bone marrow transplantation

Br J Haematol. 1995 Dec;91(4):935-7. doi: 10.1111/j.1365-2141.1995.tb05415.x.

Abstract

We report a case of peripheral primitive neuroectodermal tumour (PNET) in a 36-year-old man who 10 years earlier received an allogeneic bone marrow transplantation (BMT) for a non-Hodgkin's lymphoma. Immunohistochemistry proved definitive elimination of a relapse of the original disease and confirmed the diagnosis of PNET. The role of total body irradiation pre-BMT in the genesis of this secondary tumour is discussed. The importance of registering secondary malignant solid tumours after BMT is emphasized. To our knowledge, an Ewing family tumour following BMT has not previously been reported.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Marrow Transplantation / adverse effects*
  • Humans
  • Immunohistochemistry
  • Lymphoma, Non-Hodgkin / radiotherapy*
  • Lymphoma, Non-Hodgkin / therapy
  • Male
  • Neoplasms, Second Primary / etiology*
  • Neoplasms, Second Primary / surgery
  • Neuroectodermal Tumors, Primitive, Peripheral / etiology*
  • Neuroectodermal Tumors, Primitive, Peripheral / surgery
  • Time Factors
  • Transplantation, Homologous
  • Whole-Body Irradiation / adverse effects*