CGS 26529: the biological profile of a novel, orally active 5-lipoxygenase inhibitor with an extended duration of action

Inflamm Res. 1995 Aug:44 Suppl 2:S147-8. doi: 10.1007/BF01778305.
No abstract available

MeSH terms

  • Animals
  • Dogs
  • Female
  • Guinea Pigs
  • Humans
  • Hydroxyurea / analogs & derivatives*
  • Hydroxyurea / pharmacology
  • Hydroxyurea / toxicity
  • In Vitro Techniques
  • Injections, Intravenous
  • Isoquinolines / pharmacology*
  • Isoquinolines / toxicity
  • Lipoxygenase Inhibitors / pharmacology*
  • Lipoxygenase Inhibitors / toxicity
  • Male
  • Mice
  • Mice, Inbred AKR
  • Pleurisy / chemically induced
  • Pleurisy / prevention & control
  • Rats
  • Rats, Sprague-Dawley
  • Tetrahydroisoquinolines*

Substances

  • CGS 26529
  • Isoquinolines
  • Lipoxygenase Inhibitors
  • Tetrahydroisoquinolines
  • zileuton
  • Hydroxyurea