The objective of the current experiment was to perform a psychophysiological investigation of the interference effects of global information on the analysis of local information, and vice versa. Subjects' choice reactions to letters at one level of information in a compound letter stimulus were impaired when letters at the other (irrelevant) level signified the opposite response. In the absence of differences in processing speed, global and local information produced symmetrical interference effects. Interference effects did vary, however, as a function of temporal advantage for the processing of information from either level. The individually faster level (be it global or local) interfered with the slower level but was itself relatively immune to such interference by the slower level. Analysis of event-related brain potentials and of the electromyogram revealed that incongruent irrelevant letters induced perceptual conflict but not response competition, thus pointing to a perceptual locus of processing dominance for the faster processed level of information in the compound stimulus.