Differential diagnosis of extra-axial intracranial tumours by dynamic spin-echo MRI

Neuroradiology. 1995 Oct;37(7):522-5. doi: 10.1007/BF00593708.

Abstract

Dynamic MRI was performed on 22 patients with extra-axial intracranial tumours. Serial images were obtained every 30 s for 3 min using a spin-echo sequence (TR 200, TE 15 ms) after rapid injection of Gd-DTPA, 0.1 mmol/kg body weight. The contrast medium enhancement ratio (CER) was correlated with the histology of the tumours. Meningiomas and extra-axial metastases showed a sharp rise, then a gradual decline. Although both had a definite early peak of CER, metastases showed a more rapid decline. Neuromas and extra-axial lymphoma showed a slow, steady increase with no peak within 180 s. This study indicates that the CER is helpful in the differentiation of extra-axial tumours.

MeSH terms

  • Adult
  • Aged
  • Brain / pathology
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary
  • Contrast Media*
  • Diagnosis, Differential
  • Female
  • Gadolinium DTPA
  • Humans
  • Lymphoma / diagnosis
  • Lymphoma / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meningioma / diagnosis
  • Meningioma / pathology
  • Middle Aged
  • Neuroma / diagnosis
  • Neuroma / pathology
  • Organometallic Compounds*
  • Pentetic Acid / analogs & derivatives*

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium DTPA