IgA deficiency and psoriasis: relevance of IgA in the pathogenesis of psoriasis

P C van de Kerkhof; P M Steijlen

doi:10.1159/000246487

IgA deficiency and psoriasis: relevance of IgA in the pathogenesis of psoriasis

Dermatology. 1995;191(1):46-8. doi: 10.1159/000246487.

Authors

P C van de Kerkhof¹, P M Steijlen

Affiliation

¹ Department of Dermatology, University Hospital Nijmegen, The Netherlands.

PMID: 8589483
DOI: 10.1159/000246487

Abstract

A psoriatic patient with absolute deficiency of IgA is reported. The manifestations of psoriasis appeared at the age of 6 months and proved to be resistant to various treatments. The present case report and the data available in the literature on IgA and psoriasis all converge on the hypothesis that IgA is a systemic factor which belongs to the 'off switches' of the psoriatic process.

Publication types

Case Reports

MeSH terms

Adult
Drug Resistance
Humans
IgA Deficiency / complications*
Immunoglobulin A / analysis
Immunoglobulin A / immunology*
Infant
Male
Psoriasis / drug therapy
Psoriasis / immunology*
Psoriasis / pathology
T-Lymphocytes / pathology

Substances

Immunoglobulin A