Abstract
In several clinical centres in Germany (Berlin, Hamburg, Munich and others) a collaborative study on the genetics of asthma is being performed. It started at the beginning of 1995, when 100 nuclear families with two or more affected siblings were recruited. The participants are being characterized by interview information, methacholine challenge, peak flow variability, skin-prick test, total and specific IgE.
MeSH terms
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Adolescent
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Adult
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Asthma / diagnosis
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Asthma / epidemiology*
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Asthma / genetics*
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Asthma / physiopathology
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Bronchial Hyperreactivity / epidemiology
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Bronchial Provocation Tests
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Child
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Child, Preschool
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Forced Expiratory Volume
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Germany / epidemiology
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Humans
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Immunoglobulin E / blood
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Methacholine Chloride
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Peak Expiratory Flow Rate
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Pilot Projects
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Polymerase Chain Reaction
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Skin Tests
Substances
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Methacholine Chloride
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Immunoglobulin E