Abstract
Bioassay-directed fractionation of a methylene chloride extract of the root bark of Erythrina eriotricha resulted in the isolation of a novel isoflavanone, named eriotrichin B, and the five known pterocarpans, isonorautenol, erybraedin A, erybraedin C, erybraedin D and erybraedin E. The structure of the new compound has been investigated by extensive spectroscopic studies, including 2D NMR and chemical evidence. The in vitro antimicrobial spectrum and potencies of the isolated compounds are also reported.
Publication types
-
Comparative Study
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemistry*
-
Anti-Bacterial Agents / isolation & purification
-
Anti-Bacterial Agents / pharmacology
-
Benzofurans / chemistry*
-
Benzofurans / isolation & purification
-
Benzofurans / pharmacology
-
Erythrina*
-
Escherichia coli / drug effects
-
Escherichia coli / growth & development
-
Isoflavones / chemistry*
-
Isoflavones / isolation & purification
-
Isoflavones / pharmacology
-
Magnetic Resonance Spectroscopy
-
Mass Spectrometry
-
Methylene Chloride
-
Microbial Sensitivity Tests
-
Molecular Structure
-
Plant Extracts
-
Plant Roots
-
Plants, Medicinal*
-
Staphylococcus aureus / drug effects
-
Staphylococcus aureus / growth & development
Substances
-
Anti-Bacterial Agents
-
Benzofurans
-
Isoflavones
-
Plant Extracts
-
Methylene Chloride