Bioactive isocoumarins and related metabolites from conifer endophytes

J A Findlay; S Buthelezi; R Lavoie; L Peña-Rodriguez; J D Miller

doi:10.1021/np50125a021

Bioactive isocoumarins and related metabolites from conifer endophytes

J Nat Prod. 1995 Nov;58(11):1759-66. doi: 10.1021/np50125a021.

Authors

J A Findlay¹, S Buthelezi, R Lavoie, L Peña-Rodriguez, J D Miller

Affiliation

¹ Department of Chemistry, University of New Brunswick, Fredericton, Canada.

PMID: 8594154
DOI: 10.1021/np50125a021

Abstract

Six new [1-4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Canoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce budworm larvae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Canada
Coumarins / chemistry*
Coumarins / isolation & purification
Coumarins / toxicity
Insecticides / chemistry*
Insecticides / isolation & purification
Insecticides / toxicity
Larva
Plants, Toxic / chemistry*

Substances

Coumarins
Insecticides