Pattern of hepatitis A and hepatitis B virus markers in cases of acute sporadic hepatitis and in healthy school children from north west India

J Trop Pediatr. 1995 Dec;41(6):328-9. doi: 10.1093/tropej/41.6.328.

Abstract

The pattern of viral markers in acute sporadic hepatitis in 329 children and those in 334 healthy school children from North West India were studied. Hepatitis A was found to be the commonest infection in sporadic cases (78 per cent). Of these, 86 per cent were under 10 years and 50 per cent less than 5 years of age. Hepatitis B was positive in 8 per cent, non-A non-B in 13 per cent, A as well as B in 1 per cent, and none had Delta virus infection. Viral markers in healthy school children showed anti-HAV IgG positivity in 96 and 85 per cent in those belonging to low and high socio-economic groups, respectively, indicating past infection. HBsAg was positive in 1 per cent of cases. Viral hepatitis is an important public health problem in children and warrants active immunization.

MeSH terms

  • Adolescent
  • Biomarkers / blood
  • Child
  • Child, Preschool
  • Female
  • Hepatitis A / epidemiology
  • Hepatitis A / immunology*
  • Hepatitis Antibodies / blood*
  • Hepatitis B / epidemiology
  • Hepatitis B / immunology*
  • Hepatitis B Surface Antigens / blood
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • India / epidemiology
  • Male
  • Population Surveillance
  • Prevalence
  • School Health Services

Substances

  • Biomarkers
  • Hepatitis Antibodies
  • Hepatitis B Surface Antigens
  • Immunoglobulin G
  • Immunoglobulin M