Pulmonary sarcoidosis coexisting with systemic lupus erythematosus

Scand J Rheumatol. 1996;25(2):109-11. doi: 10.3109/03009749609069219.

Abstract

A 23 year old female presented with fatigue, Raynaud's syndrome, symmetric polyarthritis, lymphocytopenia, hypocomplementemia, IgG elevation, and antinuclear antibodies with anti-U1RNP specificity. A diagnosis of systemic lupus erythematosus (SLE) was made. Disseminated micronodular infiltration in the chest X-ray, a pattern of lymphocytic alveolitis by bronchoalveolar lavage, histologic demonstration of non-caseating epitheloid microgranulomas, and rapid reversal of lung disease upon low-dose methylprednisolone treatment led to a diagnosis of concomitant sarcoidosis. Clues to the diagnosis of sarcoidosis coexisting with SLE are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • CD4-CD8 Ratio
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / complications*
  • Radiography
  • Sarcoidosis, Pulmonary / complications*
  • Sarcoidosis, Pulmonary / diagnosis
  • Sarcoidosis, Pulmonary / diagnostic imaging