Granulocyte-macrophage colony-stimulating factor accelerates growth of Lewis lung carcinoma in mice

Cancer Lett. 1996 Mar 29;101(2):193-7. doi: 10.1016/0304-3835(96)04134-1.

Abstract

Granulocyte-macrophage colony-stimulating factor (GM-CSF) has not been found to exert any influence on the proliferation of Lewis lung carcinoma (LLC) cells in vitro. Nevertheless, when administered intraperitoneally, GM-CSF accelerated the growth of subcutaneously growing LLC in mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carcinoma, Lewis Lung / pathology*
  • Cell Division / drug effects
  • Female
  • Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology*
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred DBA

Substances

  • Granulocyte-Macrophage Colony-Stimulating Factor