Abstract
1-¿[(5-Nitro-2-furyl)methylene]amino¿-1,2,4-triazole, C7H5N5O3, is a new analogue of nifurtimox with activity against Tripanosoma cruzi. In the crystal structure, the molecule lies on a mirror plane and has an E-sZ conformation along the N = C-C moiety. The molecules are linked through C-H...O and C-H...N interactions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiprotozoal Agents / chemistry*
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Crystallography, X-Ray
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Imines / chemistry*
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Molecular Conformation
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Molecular Structure
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Nifurtimox / analogs & derivatives*
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Triazoles / chemistry*
Substances
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Antiprotozoal Agents
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Imines
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Triazoles
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1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole
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Nifurtimox