Inhibitors of trypanothione reductase as potential antitrypanosomal drugs

Biochem Soc Trans. 1995 Nov;23(4):511S. doi: 10.1042/bst023511s.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Binding Sites
  • Drug Design
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Glutathione / analogs & derivatives
  • Glutathione / metabolism
  • Glutathione Disulfide
  • Humans
  • NADH, NADPH Oxidoreductases / antagonists & inhibitors*
  • NADH, NADPH Oxidoreductases / chemistry
  • NADH, NADPH Oxidoreductases / metabolism
  • Phenothiazines / chemistry
  • Phenothiazines / pharmacology
  • Spermidine / analogs & derivatives
  • Spermidine / metabolism
  • Trypanocidal Agents / chemistry
  • Trypanocidal Agents / pharmacology*

Substances

  • Enzyme Inhibitors
  • Phenothiazines
  • Trypanocidal Agents
  • trypanothione
  • NADH, NADPH Oxidoreductases
  • trypanothione reductase
  • Glutathione
  • Spermidine
  • Glutathione Disulfide