Regional assignment of human ESTs by whole-genome radiation hybrid mapping

Mamm Genome. 1996 Jun;7(6):446-50. doi: 10.1007/s003359900130.

Abstract

The UK HGMP Resource Centre's collection of human partial cDNA sequences (ESTs) have been examined for suitability for mapping by PCR on a panel of somatic cell hybrids. The chromosomal assignments of 92 ESTs were determined with a monochromosomal hybrid panel, and a subset of 45 were linked to genetic markers with a panel of whole-genome radiation hybrids (WG-RHs). These results demonstrate the potential of WG-RHs to construct a transcript map of the human genome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Chromosome Mapping
  • DNA Primers
  • DNA, Complementary / genetics
  • Genome*
  • Humans
  • Hybrid Cells / radiation effects
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Tagged Sites*

Substances

  • DNA Primers
  • DNA, Complementary

Associated data

  • GENBANK/L25081
  • GENBANK/M11526
  • GENBANK/M18457
  • GENBANK/M27436
  • GENBANK/M81457
  • GENBANK/M86521
  • GENBANK/X02905
  • GENBANK/X07743
  • GENBANK/X67247
  • GENBANK/X72066
  • GENBANK/Z19654
  • GENBANK/Z19684
  • GENBANK/Z19780
  • GENBANK/Z19789
  • GENBANK/Z19810
  • GENBANK/Z19870
  • GENBANK/Z20044
  • GENBANK/Z20046
  • GENBANK/Z20058
  • GENBANK/Z20165
  • GENBANK/Z20188
  • GENBANK/Z20198
  • GENBANK/Z20199
  • GENBANK/Z20319
  • GENBANK/Z20346
  • GENBANK/Z20374
  • GENBANK/Z20424
  • GENBANK/Z20767
  • GENBANK/Z20890
  • GENBANK/Z21329