Involvement of phosphatidylinositol 3-kinase in the activation of p70 S6 kinase by the T cell costimulatory molecule CD28

Biochem Soc Trans. 1996 Feb;24(1):88S. doi: 10.1042/bst024088s.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / pharmacology
  • CD28 Antigens / immunology
  • CD28 Antigens / physiology*
  • Cell Line
  • Enzyme Activation
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Kinetics
  • Lymphocyte Activation
  • Phosphatidylinositol 3-Kinases
  • Phosphatidylinositol Phosphates / metabolism
  • Phosphotransferases (Alcohol Group Acceptor) / metabolism*
  • Polyenes / pharmacology
  • Protein Serine-Threonine Kinases / metabolism*
  • Ribosomal Protein S6 Kinases
  • Sirolimus
  • T-Lymphocytes / immunology
  • T-Lymphocytes / physiology*
  • Tetradecanoylphorbol Acetate / pharmacology

Substances

  • Antibodies, Monoclonal
  • CD28 Antigens
  • Immunosuppressive Agents
  • Phosphatidylinositol Phosphates
  • Polyenes
  • phosphatidylinositol 3,4,5-triphosphate
  • Phosphotransferases (Alcohol Group Acceptor)
  • Protein Serine-Threonine Kinases
  • Ribosomal Protein S6 Kinases
  • Tetradecanoylphorbol Acetate
  • Sirolimus