Concentration-dependent mutational hotspots induced by the antineoplastic drug chloroethyl-cyclohexyl-nitroso-urea in mammalian cells

Mutat Res. 1996 Jun 10;352(1-2):47-9. doi: 10.1016/0027-5107(95)00226-X.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents, Alkylating / toxicity*
  • Cell Line
  • Genes, Suppressor / genetics
  • Haplorhini
  • Lomustine / toxicity*
  • Mutagenesis
  • Mutation / genetics*
  • RNA, Transfer / genetics

Substances

  • Antineoplastic Agents, Alkylating
  • supF tRNA
  • Lomustine
  • RNA, Transfer