Comparison of occurrence of genetic syndromes in ventricular septal defect with pulmonic stenosis (classic tetralogy of Fallot) versus ventricular septal defect with pulmonic atresia

M C Digilio; B Marino; S Grazioli; D Agostino; A Giannotti; B Dallapiccola

doi:10.1016/s0002-9149(96)00212-3

Comparison of occurrence of genetic syndromes in ventricular septal defect with pulmonic stenosis (classic tetralogy of Fallot) versus ventricular septal defect with pulmonic atresia

Am J Cardiol. 1996 Jun 15;77(15):1375-6. doi: 10.1016/s0002-9149(96)00212-3.

Authors

M C Digilio¹, B Marino, S Grazioli, D Agostino, A Giannotti, B Dallapiccola

Affiliation

¹ Department of Pediatric Cardiology, Bambino Gesu Hospital, Rome, Italy.

PMID: 8677886
DOI: 10.1016/s0002-9149(96)00212-3

Abstract

Our results confirm that classic TF can be associated with many genetic conditions, but most patients are nonsyndromic. In contrast, children with TF-PA have a high incidence of genetic syndromes, particularly those related to CATCH22 syndrome.

Publication types

Comparative Study

MeSH terms

Abnormalities, Multiple / epidemiology
Abnormalities, Multiple / genetics*
Case-Control Studies
Child, Preschool
Chromosome Deletion*
Chromosomes, Human, Pair 22*
Female
Heart Septal Defects, Ventricular / genetics*
Humans
Incidence
Male
Prevalence
Pulmonary Atresia / genetics*
Syndrome
Tetralogy of Fallot / genetics*