Recurrent Goodpasture's disease

Am J Kidney Dis. 1996 Apr;27(4):573-8. doi: 10.1016/s0272-6386(96)90169-9.

Abstract

Goodpasture's disease is usually a monophasic illness that can be successfully treated in a large proportion of patients. Recurrent disease is rare. We report a case of Goodpasture's disease in which recurrent pulmonary hemorrhage and glomerulonephritis were observed over 12 years. Antiglomerular basement membrane autoantibody was monitored throughout this period, and we demonstrate the close association of antibody levels with disease recurrence.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Anti-Glomerular Basement Membrane Disease / diagnosis*
  • Anti-Glomerular Basement Membrane Disease / pathology
  • Antibodies / blood
  • Autoantibodies
  • Basement Membrane / immunology
  • Biopsy
  • Chronic Disease
  • Follow-Up Studies
  • Humans
  • Kidney / pathology
  • Kidney Glomerulus / immunology
  • Male
  • Recurrence

Substances

  • Antibodies
  • Autoantibodies
  • antiglomerular basement membrane antibody