Abstract
The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted protein-coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / chemistry
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Bacterial Proteins / genetics*
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Base Composition
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Base Sequence
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Biological Transport / genetics
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Carbon Dioxide / metabolism
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Chromosome Mapping
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Chromosomes, Bacterial / genetics
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DNA Replication
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DNA, Bacterial / genetics*
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Databases, Factual
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Energy Metabolism / genetics
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Genes, Bacterial
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Genome, Bacterial*
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Hydrogen / metabolism
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Methane / metabolism
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Methanococcus / genetics*
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Methanococcus / physiology
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Molecular Sequence Data
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Protein Biosynthesis
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Sequence Analysis, DNA
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Transcription, Genetic
Substances
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Bacterial Proteins
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DNA, Bacterial
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Carbon Dioxide
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Hydrogen
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Methane
Associated data
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GENBANK/L77118
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GENBANK/L77119
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GENBANK/U67459
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GENBANK/U67460
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GENBANK/U67461
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GENBANK/U67462
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GENBANK/U67463
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GENBANK/U67464
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GENBANK/U67465
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GENBANK/U67466
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GENBANK/U67467
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GENBANK/U67468
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GENBANK/U67469
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GENBANK/U67470
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GENBANK/U67471
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GENBANK/U67472
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GENBANK/U67473
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GENBANK/U67474
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GENBANK/U67475
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GENBANK/U67476
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GENBANK/U67477
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GENBANK/U67478
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GENBANK/U67479
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GENBANK/U67480
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GENBANK/U67481
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GENBANK/U67482
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GENBANK/U67483
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GENBANK/U67484
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GENBANK/U67485
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GENBANK/U67486