Abstract
New series of monobactam antibiotics, bearing thio-and dithiocarbamate derivatives as C-4 side chain, were synthesized. Some compounds were found to have good antibacterial activity against Gram-negative bacteria.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemical synthesis*
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Anti-Bacterial Agents / pharmacology
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Bacteria / drug effects
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Gram-Negative Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Microbial Sensitivity Tests
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Monobactams / chemical synthesis*
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Monobactams / pharmacology
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Thiocarbamates / chemical synthesis*
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Thiocarbamates / pharmacology
Substances
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Anti-Bacterial Agents
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Monobactams
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Thiocarbamates