Bayesian estimates of disease maps: how important are priors?

Stat Med. 1995 Nov;14(21-22):2411-31. doi: 10.1002/sim.4780142111.

Abstract

In the fully Bayesian (FB) approach to disease mapping the choice of the hyperprior distribution of the dispersion parameter is a key issue. In this context we investigated the sensitivity of the rate ratio estimates to the choice of the hyperprior via a simulation study. We also compared the performance of the FB approach to mapping disease risk to the conventional approach of mapping maximum likelihood (ML) estimates and p-values. The study was modelled on the incidence data of insulin dependent diabetes mellitus (IDDM) as observed in the communes of Sardinia.

MeSH terms

  • Bayes Theorem*
  • Cluster Analysis*
  • Computer Simulation
  • Data Interpretation, Statistical
  • Diabetes Mellitus, Type 1 / epidemiology
  • Incidence
  • Italy / epidemiology
  • Models, Statistical*
  • Poisson Distribution
  • Risk*