Event-time analysis of the effect of season of parturition, parity, and concurrent disease on parturition-to-conception interval in dairy cows

Am J Vet Res. 1996 May;57(5):640-5.

Abstract

Objective: To quantify the effect of season of parturition, parity, and various diseases on time to conception.

Design: Event-time analysis (survival analysis).

Sample population: 44,450 cows delivering calves between September 1985 and September 1986, from 6,227 Ayrshire dairy herds in 80 Finnish communities.

Procedures: Primiparous and multiparous cows were analyzed in separate Cox proportional hazards models for postpartum days 56 to 120. Occurrence of 43 diseases or disorders was recorded; codes were condensed into 25 variables offered to each model. Season of parturition was categorized into spring, summer, and fall-winter; for multiparous cows, 3 categorical variables represented parity. Models controlled for 60-day milk and milk fat production, herd milk production, and community. For all observations, parturition-to-conception interval was plotted against calendar day of parturition.

Results: For multiparous cows, parturition in the spring or summer and being of parity 2 or 3-4 (vs older) increased the chance of conceiving; 10 diseases or disorders decreased this probability. Similarly, in the model for primiparae, parturition in spring or summer increased the probability of conception, and 6 disorders decreased it. Disorders that were detrimental in both models were anestrus, ovulatory dysfunction, other infertility, late metritis, and clinical ketosis.

Conclusions: The effect of season on the parturition-to-conception interval was marked at this latitude. Parturition during late April, causing confluence of postpartum day 55 with the summer solstice, was associated with the shortest parturition-to-conception intervals. Ketosis was found to be an important factor in lengthening the parturition-to-conception interval, highlighting the effect of negative energy balance on postpartum restoration of reproductive function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cattle / metabolism
  • Cattle / physiology*
  • Cattle Diseases / epidemiology
  • Cattle Diseases / physiopathology*
  • Female
  • Fertilization / physiology*
  • Incidence
  • Infertility, Female / epidemiology
  • Infertility, Female / physiopathology
  • Infertility, Female / veterinary
  • Ketosis / epidemiology
  • Ketosis / physiopathology
  • Ketosis / veterinary
  • Labor, Obstetric / physiology*
  • Mastitis, Bovine / epidemiology
  • Mastitis, Bovine / physiopathology
  • Milk / metabolism
  • Ovulation / physiology
  • Parity / physiology*
  • Pregnancy
  • Proportional Hazards Models
  • Seasons*
  • Survival Analysis
  • Time Factors