Abstract
The whole plants of Ajuga lupulina afforded five compounds, including three new clerodane diterpenes, lupulins A-C (1-3), whose structures were elucidated by spectral methods. Among these compounds, lupulins A (1) and B (2) as well as the acid hydrolysate (5) of lupulin D (4) showed antibacterial activities against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetals / chemistry
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Acetals / isolation & purification*
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Acetals / pharmacology
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Bacteria / drug effects*
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China
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Diterpenes / chemistry
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Diterpenes / isolation & purification*
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Diterpenes / pharmacology
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Escherichia coli / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Plants, Medicinal / chemistry*
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Pseudomonas aeruginosa / drug effects
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Spectroscopy, Fourier Transform Infrared
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Staphylococcus aureus / drug effects
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Triterpenes / chemistry
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Triterpenes / isolation & purification*
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Triterpenes / pharmacology
Substances
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Acetals
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Anti-Bacterial Agents
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Diterpenes
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Triterpenes