Immunochemical detection of drug-protein adducts in acetaminophen hepatotoxicity

Adv Exp Med Biol. 1996:387:47-55. doi: 10.1007/978-1-4757-9480-9_7.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetaminophen / chemistry
  • Acetaminophen / metabolism
  • Acetaminophen / toxicity*
  • Analgesics, Non-Narcotic / chemistry
  • Analgesics, Non-Narcotic / metabolism
  • Analgesics, Non-Narcotic / toxicity*
  • Animals
  • Blotting, Western
  • Chemical and Drug Induced Liver Injury / metabolism*
  • Chemical and Drug Induced Liver Injury / pathology
  • Chromatography, Ion Exchange
  • Cysteine / chemistry
  • Cytosol / metabolism
  • Immunohistochemistry
  • Liver / metabolism
  • Liver / pathology
  • Male
  • Mice
  • Mice, Inbred Strains
  • Proteins / chemistry
  • Proteins / metabolism*
  • Selenium / pharmacology

Substances

  • Analgesics, Non-Narcotic
  • Proteins
  • Acetaminophen
  • Selenium
  • Cysteine